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Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of therapies in palliative care.
Reviewed September 2009
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| Title: |
Second-line chemotherapy in advanced and metastatic CRC
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Patients with metastatic or advanced colorectal cancer are often treated with chemotherapy. If the disease doesn't improve with a specific chemotherapy regimen, a different chemotherapy regimen may be tried, called second-line treatment, with the aim to...
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| Date: |
Apr 2009
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| Title: |
Palliative biliary stents for obstructing pancreatic carcinoma
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The majority of patients with cancer of the pancreas are diagnosed only after blockage of the bile ducts has occurred. Surgical by-pass (SBP) or endoscopic stenting (ES) of the blockage are the treatment options available for these patients. This review...
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| Date: |
Mar 2009
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| Title: |
Haloperidol for the treatment of nausea and vomiting in palliative care patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
We did not identify any randomised controlled trials (RCTs) to find out if haloperidol is a useful drug for the treatment of nausea or vomiting in palliative care patients. Nausea and vomiting are common problems for patients with serious life threateni...
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| Date: |
Jan 2009
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| Title: |
Medically assisted nutrition for palliative care in adult patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
It is common for palliative care patients to have reduced oral intake during their illness. Management of this condition includes discussion with the patient, family and staff involved and may include giving nutrition with medical assistance. This can b...
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| Date: |
Jul 2008
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| Title: |
Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is the most common neurodegenerative disorder of the motor system in adults. Pain is a frequent symptom and may have a pronounced impact on quality of life and suffering. Des...
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| Date: |
Mar 2008
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| Title: |
Medically assisted hydration for adult palliative care patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
It is common for palliative care patients to have reduced fluid intake during their illness. Management of this condition includes discussion with the patient, family and staff involved and may include the provision of fluids with medical assistance. Th...
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| Date: |
Feb 2008
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| Title: |
Psychotherapy for depression among incurable cancer patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Depressive states represent frequent complications among cancer patients and are more common amongst advanced cancer patients. Psychotherapy comprises of various interventions for ameliorating or preventing psychological distress conducted by direct ver...
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| Date: |
Feb 2008
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| Title: |
Palliative endobronchial brachytherapy for non-small cell lung cancer
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Patients with inoperable non-small cell lung cancer (NSCLC) have a poor prognosis and the therapeutic options are limited to controlling their symptoms and maintaining their quality of life. Palliative endobronchial brachytherapy (EBB) is used as a trea...
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| Date: |
Dec 2007
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| Title: |
Interventions for noisy breathing in patients near to death
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Approximately half of those relatives and friends who witness it, as well as hospital staff, find the noise of 'death rattle' distressing. For this reason, doctors and nurses try to eliminate the sound using a variety of methods, from changing the posit...
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| Date: |
Nov 2007
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| Title: |
Methadone for cancer pain
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Pain is a common and debilitating symptom of cancer. Methadone is an opioid drug used to treat cancer pain, and can be given by mouth as liquid, tablet or capsule, via the rectum as a suppository, or injected into the vein, muscle or under the skin. Thi...
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| Date: |
Aug 2007
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| Title: |
Ketamine as an adjuvant to opioids for cancer pain
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The benefits and harms of adding ketamine to strong pain-killers such as morphine for the relief of cancer pain are not yet established. Morphine-like drugs (opioids) are frequently prescribed for moderate and severe cancer pain, but in some cases these...
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| Date: |
Jun 2007
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| Title: |
Interventions for dysphagia in oesophageal cancer
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Most patients with oesophageal cancer undergo palliative treatment due to diagnosis at an advanced stage. The optimal palliative technique for dysphagia is not established despite significant progress in endoscopic techniques. The main objective of pall...
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| Date: |
May 2007
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| Title: |
Oxygen therapy for dyspnoea in adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review aimed to determine if oxygen therapy relieves breathlessness in end-stage illness in adults. No overall improvement of breathlessness in cancer study participants was found when oxygen breathing was compared to air breathing. However, some c...
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| Date: |
Apr 2007
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| Title: |
Laxatives for the management of constipation in palliative care patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
There remains insufficient randomised controlled trial data to determine the 'best' management of constipation in palliative care. Constipation is commonly experienced by palliative care patients as a result of the use of medications, such as opioids fo...
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| Date: |
Aug 2006
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| Title: |
Palliative radiotherapy regimens for non-small cell lung cancer
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
In most developed countries lung cancer is one of the commonest tumours. Only 10 to 20% of patients can have surgery with a chance of cure. For many of the rest it can be beneficial to treat the tumour in the lung with radiotherapy to relieve symptoms s...
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| Date: |
Aug 2006
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| Title: |
Drug therapy for anxiety in adult palliative care patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Currently there is no evidence on the role of drugs in the treatment of anxiety associated with terminal illness. Anxiety is a common symptom associated with patients near the end of life. As with other areas of palliative care, the majority of availabl...
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| Date: |
Oct 2003
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