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Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for managing high blood pressure.
Reviewed September 2009
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| Title: |
Roselle for hypertension in adults
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Hypertension is a serious health problems worldwide. Controlling and lowering blood pressure have a significant benefit to the hypertensive patients because hypertension is a risk factor for stroke, heart disease and cardiovascular disease. A tropical p...
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| Date: |
Oct 2009
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| Title: |
Blood pressure lowering efficacy of reserpine for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Reserpine, a root extract of the naturally occurring plant Rauwolfia serpentina, was used in the past as first-line therapy for reducing blood pressure. Nowadays, it is used mainly as a second line agent. This review, which aimed to find and summarize e...
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| Date: |
Aug 2009
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| Title: |
Blood pressure lowering efficacy of loop diuretics for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Loop diuretics are more commonly used to reduce water retention, but are also indicated to lower elevated blood pressure. We asked how much this class of drugs lowers blood pressure and whether there is a difference between individual drugs within the c...
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| Date: |
Aug 2009
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| Title: |
Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Coenzyme Q10 has been studied as a potential treatment for hypertension, a common medical condition. However, there is not enough reliable evidence to show whether or not it can be a useful medication to lower blood pressure. A systematic review was con...
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| Date: |
Aug 2009
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| Title: |
Blood pressure lowering efficacy of alpha blockers for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
The class of drugs called alpha blockers is sometimes used to lower elevated blood pressure. This class includes drugs such as doxazosin (brand name: Cardura), prazosin (Minipress) and terazosin (Hytrin). We asked how much this class of drugs lowers blo...
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| Date: |
Aug 2009
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| Title: |
Methyldopa for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Methyldopa is a medication that has been used to treat high blood pressure since the 1960s. While there is some belief methyldopa reduces blood pressure, there are concerns due to the potential for this drug to cause adverse effects. The aim of this rev...
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| Date: |
Aug 2009
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| Title: |
Treatment of hypertension in peripheral arterial disease
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
When blood pressure is consistently high, it can lead to complications such as a heart attack (myocardial infarction) or stroke. Both peripheral arterial disease (PAD) and hypertension are associated with atherosclerosis, which is hardening of the arter...
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| Date: |
Jun 2009
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| Title: |
Pharmacotherapy for hypertension in the elderly
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Hypertension (high blood pressure) is common among elderly people and increases the risk of heart attack and stroke. An assessment of all the trials of blood pressure lowering therapy in people with hypertension 60 years and over showed that treatment r...
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| Date: |
Jun 2009
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| Title: |
Long-term effects of weight-reducing drugs in hypertensive patients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
For overweight patients with elevated blood pressure doctors often recommend weight reduction. Drugs such as orlistat, sibutramine or rimonabant are sometimes suggested to assist in weight reduction and blood pressure reduction. Orlistat and sibutramine...
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| Date: |
May 2009
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| Title: |
First-line drugs for hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
One of the most important decisions in treating people with elevated blood pressure is what drug class is used first. This decision has enormous consequences in terms of health outcomes and cost. In this review health outcomes resulting from 4 drug clas...
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| Date: |
Apr 2009
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| Title: |
Endothelin receptor antagonists for pulmonary arterial hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Endothelin receptor antagonists have recently been proposed as an alternative to traditional therapies for pulmonary arterial hypertension. This updated review included eleven trials and 1457 participants in total. Endothelin receptor antagonists can im...
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| Date: |
Dec 2008
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| Title: |
Treatment blood pressure targets for hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
High blood pressure (BP) is linked to an increased risk of heart attack and stroke. High BP has been defined as any number larger than 140 to 160 /90 to 100 mmHg and as a result this range of BPs has become the standard blood pressure target for physici...
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| Date: |
Oct 2008
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| Title: |
Antihypertensive treatment for kidney transplant recipients
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
In some patient groups, different blood pressure lowering drugs have differing relative beneficial and harmful effects in addition to their blood pressure lowering action. We investigated whether different classes of drugs might have different relative ...
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| Date: |
Sep 2008
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| Title: |
Blood pressure lowering efficacy of renin inhibitors for primary hypertension
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Elevated blood pressure or hypertension can lead to heart attacks and stroke. A new class of drugs called renin inhibitors are indicated for the treatment of hypertension. Aliskiren is a member of this new class and is the only one studied [or approved]...
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| Date: |
Aug 2008
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