Systematic Reviews of Treatments for Drug Addiction

Follow the links below to find systematic reviews of the evidence for the effectiveness of treatments for drug addiction.

Created September 2009

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18 Resources Found
Results 1 to 18 displayed.
Title:   Opioid antagonists with minimal sedation for opioid withdrawal
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Opioid antagonists induce withdrawal by displacing opioids from their receptors. Adrenergic agonists, acting through non-opioid mechanisms, can reduce withdrawal symptoms induced by antagonists. The use of these substances in combination is a feasible a...
Date:   Jan 2009
Title:   Alpha2-adrenergic agonists for the management of opioid withdrawal
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Opioid withdrawal is similar with alpha2-adrenergic agonists and reducing doses of methadone but people stay in treatment longer with methadone and have fewer adverse effects.Managed withdrawal of opioids, or detoxification, is a required first step for...
Date:   Oct 2008
Title:   Detoxification treatments for opiate dependent adolescents
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Substance abuse among adolescents (13 to 18 years old) is a serious and growing problem. It is important to identify effective treatments for those who are opioid dependent. For adults, pharmacotherapy is a necessary and acceptable part of effective tre...
Date:   Oct 2008
Title:   Inpatient versus other settings for detoxification for opioid dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Dependence on opioid drugs, such as heroin, morphine, and codeine, is a serious problem in many societies. Opioids are very difficult to quit using. The first step to quitting is detoxification, which can cause a number of painful symptoms as the drug w...
Date:   May 2008
Title:   Maintenance treatments for opiate dependent adolescent
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   It is difficult to draw conclusions about the use of maintenance pharmacological interventions from only two trials. Substance abuse among adolescents (13 to 18 years old) is a serious and growing problem. The most common drugs used by young people worl...
Date:   Mar 2008
Title:   Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Buprenorphine can reduce heroin use compared with placebo, although it is less effective than methadone. Methadone is widely used as a replacement for heroin in medically-supported maintenance or detoxification programs. Two other drugs are sometimes us...
Date:   Dec 2007
Title:   Psychosocial interventions for pregnant women in outpatient illicit drug treatment programs compared to other interventions
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   The effectiveness of psychosocial interventions in pregnant women enrolled in illicit drug treatment programs.Women who use illicit drugs while pregnant are more likely to give birth early and have low weight infants that are at risk of neonatal abstine...
Date:   Aug 2007
Title:   Antidepressants for cocaine dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   As dependence on cocaine became more common and caused major personal and social problems, several methods have been tried to help reduce dependence. Antidepressants are often tried to help people manage the depression and cravings that occur when peopl...
Date:   Jul 2007
Title:   Psychosocial interventions for cocaine and psychostimulant amphetamines related disorders
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Psychostimulants such as amphetamines and cocaine are used, at least in part, because of their effects on mood, cognition and behaviour. People who abuse or are dependent on them often have a long history of repeated periods of intoxication and of withd...
Date:   May 2007
Title:   Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Drugs that block opioids are sometimes given to opioid dependent people while they are under heavy sedation or anaesthesia to speed up withdrawal. The review of trials shows that this sort of withdrawal treatment is quicker than withdrawal managed with ...
Date:   Nov 2005
Title:   Oral naltrexone maintenance treatment for opioid dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Methadone treatment is widely used for detoxification or long-term maintenance therapy of opioid users to reduce harm and improve health and social outcomes yet relapses to illicit drug use are common. Naltrexone is an opioid antagonist that has no euph...
Date:   Oct 2005
Title:   Heroin maintenance for chronic heroin dependents
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Heroin users who are trying to quit are often given maintenance medications such as methadone, buprenorphine, and levo-alpha-acetyl-methadol (LAAM). Maintenance medications may help long-term heroin users resume a normal life more easily and with less c...
Date:   Feb 2005
Title:   Treatment for Methaqualone dependence in adults
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Dependence and abuse of methaqualone, a type of sedative-hypnotic, is a major public health problem in parts of Africa and India. Treatment is highly variable and takes place in both in-patient and out-patient settings. Despite an extensive search of el...
Date:   Feb 2005
Title:   Psychosocial treatment for opiate abuse and dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Psychosocial interventions alone are offered to people with opiate use disorders indiscriminately across countries; sometimes representing the most prevalent treatment after substitution therapy. Despite its wide use in clinical practice, no systematic ...
Date:   Aug 2004
Title:   Dopamine agonists for cocaine dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cocaine is a major drug of abuse. Cocaine dependence is a common and serious condition, which has become nowadays a substantial public health problem. There is a wide and well documented range of consequences associated to chronic use of this drug, such...
Date:   Feb 2003
Title:   Carbamazepine for cocaine dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Cocaine use has become a substantial health problem in the United States and some South American countries. Cocaine dependence involves a number of medical, psychological and social problems, including the spread of infectious diseases and violence. car...
Date:   Feb 2003
Title:   LAAM maintenance vs methadone maintenance for heroin dependence
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   Opiate drugs are used to help people reduce their dependence on heroin (an opiate drug). Methadone needs daily doses, but the effects do not last 24 hours for many people. A dose of LAAM (levomethadyl acetate hydrochloride) works for two or three days. ...
Date:   Feb 2002
Title:   Treatment for amphetamine dependence and abuse
Publisher:   John Wiley and Sons, Ltd. for The Cochrane Collaboration
Description:   As amphetamines can produce feelings of euphoria, they are widely manufactured. Dependence on amphetamines is more common than cocaine and heroin dependence combined, and ending dependence on amphetamines can be as difficult as it is for cocaine and her...
Date:   Aug 2001
Results 1 to 18 displayed.