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Follow the links below to find summaries of systematic reviews of the evidence for the effectiveness of treatments for bipolar disorder.
Reviewed September 2009
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| Results 1 to 10 displayed. |
| Title: |
Olanzapine in long-term treatment for bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Bipolar affective disorder is a severe and common mental illness, characterised by periods of mania, depression and "mixed episodes" (or "dysphoric mania": a mixture of manic and depressed symptoms).
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| Date: |
Jan 2009
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| Title: |
Omega-3 fatty acids for bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This systematic review investigated the efficacy of omega-3 fatty acids for bipolar disorder. Five randomised controlled trials met inclusion criteria for the review. Only one trial provided data that could be analysed, investigating ethyl-EPA as an adj...
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| Date: |
Feb 2008
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| Title: |
Oxcarbazepine in the maintenance treatment of bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Some studies have suggested that oxcarbazepine, an anti-convulsant, may have a role in preventing episode recurrence in bipolar affective disorder. This systematic review investigated the efficacy and acceptability of oxcarbazepine compared to placebo a...
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| Date: |
Nov 2007
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| Title: |
Family interventions for bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Drug treatments are the primary treatment for bipolar disorder. Alone, however, they are not sufficient to manage the disorder. Studies on psychosocial interventions for mental disorders such as schizophrenia and anxiety show that they are effective tre...
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| Date: |
Aug 2007
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| Title: |
Interventions for helping people recognise early signs of recurrence in bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
Bipolar disorder (BPD), or manic-depressive psychosis, is a common and severe mental illness, with a lifetime prevalence of 1-2%. BPD is characterised by two types of recurrence, mania and depression. High rates of recurrence and associated adverse cons...
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| Date: |
Oct 2006
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| Title: |
Lithium versus antidepressants in the long-term treatment of unipolar affective disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This systematic review investigated the efficacy and tolerability of lithium compared to antidepressants for the long-term treatment of unipolar affective disorder. Eight randomised studies (reporting on 475 participants) were included in the review. We...
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| Date: |
Aug 2006
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| Title: |
Topiramate for acute affective episodes in bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This systematic review investigated the efficacy and acceptability of topiramate compared to placebo and other agents in the treatment of acute affective episodes in bipolar disorder. One randomised controlled trial met the inclusion criteria for the re...
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| Date: |
Aug 2005
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| Title: |
Valproate for acute mood episodes in bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This systematic review investigated the efficacy and acceptability of valproate compared to that of placebo, lithium, carbamazepine, olanzapine and haloperidol in the treatment of acute episodes of bipolar disorder. Ten randomised studies were included ...
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| Date: |
Sep 2002
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| Title: |
Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This review investigated the efficacy and acceptability of valproate compared to placebo and other mood stabilisers in the maintenance treatment of bipolar disorder. Only one randomised controlled trial met the inclusion criteria for the review. This tr...
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| Date: |
Mar 2001
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| Title: |
Lithium for maintenance treatment of mood disorders
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| Publisher: |
John Wiley and Sons, Ltd. for The Cochrane Collaboration
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| Description: |
This systematic review investigated the efficacy of lithium compared to that of placebo in the maintenance treament of mood disorders (unipolar and bipolar disorder). Nine randomised studies (reporting on 825 participants) were included in the review. L...
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| Date: |
Mar 2001
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| Results 1 to 10 displayed. |
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